Cord Blood Atherogenic Index in Preeclampsia: Tracing Fetal Origins of Adult Disease
نویسندگان
چکیده
منابع مشابه
Fetal origins of adult disease
Several decades of research have demonstrated that significant contributions to risk of cardiovascular disease are made by adult lifestyle factors such as smoking, high consumption of saturated fats and salt, low levels of physical activity, and obesity. The more recent assertion that the risk of hypertension and coronary heart disease in adult life may be determined by an adverse environment b...
متن کاملAtherogenic Index of Plasma (AIP): A marker of cardiovascular disease
Background: Cardiovascular disease (CVD) is the cause of one third of deaths worldwide and this will progress because of increasing CVD's risk factors. The most basic task of dealing with the epidemic of CVD is primary prevention of risk factors. As Atherogenic Index of Plasma (AIP) is a strong marker to predict the risk of atherosclerosis and coronary heart disease, we assessed the correlat...
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BACKGROUND Severe malarial anemia (SMA) remains a major cause of pediatric illness and mortality in Sub-Saharan Africa. Here we test the hypothesis that prenatal exposures, reflected by soluble inflammatory mediators in cord blood, can condition an individual's susceptibility to SMA. METHODS In a Tanzanian birth cohort (n = 743), we measured cord blood concentrations of tumor necrosis factor ...
متن کاملFetal origins of adult disease: epidemiology and mechanisms.
The past 10 years have provided unequivocal evidence that there are associations between birth size measures and future development of adult diseases, such as type 2 diabetes and coronary artery disease. Despite initial concern that bias or residual confounding in the analyses had produced these rather bizarre associations, the findings have now been reproduced in different cohorts by independe...
متن کاملPreeclampsia and adiponectin in cord blood.
AIMS To compare cord blood concentrations of total adiponectin in the offspring of pregnancies with and without preeclampsia. METHODS Using a Luminex analyzer, cord blood adiponectin was measured in 182 singleton pregnancies with preeclampsia and compared to adiponectin measured in 511 singleton pregnancies without preeclampsia. RESULTS Adiponectin levels in cord blood increased with increa...
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ژورنال
عنوان ژورنال: Research Journal of Obstetrics and Gynecology
سال: 2012
ISSN: 1994-7925
DOI: 10.3923/rjog.2012.4.7